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  • Case Title: Metachronous Colon Cancer
  • Final Diagnosis: Moderately Differentiated Adenocarcinoma of Colon (Node Negative, T2N0M0)

Patient Profile
  • Age/Sex: 59-year-old male
Presenting Complaints:
  • Anemia
  • Mild weight loss and generalized weakness

Initial Evaluation
  • Stool Occult Blood: Positive
Colonoscopy Findings:
  • Mass lesion at the splenic flexure (suggestive of colon cancer)
  • 10–12 polyps distributed along the right colon
  • PET-CT Scan: Node-negative localized disease

First Surgery
  • Procedure Performed: Laparoscopic Left Hemicolectomy with Diverting Loop Ileostomy
  • Position: Supine with right tilt
  • Specimen Retrieval: Through a small epigastric incision
  • Histopathology: Moderately differentiated adenocarcinoma
Postoperative Course:
  • Ileostomy closure after 5 weeks
  • Recovery: Uneventful
  • Status: Patient remained well post-procedure

Second Presentation (8 Months Later)
  • Symptoms: Rectal bleeding with a drop in hemoglobin
  • Colonoscopy Findings: New tumor in the cecum
  • PET-CT: Node-negative localized disease

Second Surgery
  • Procedure: Total Colectomy (Open Surgery)
  • Recovery: Smooth and uneventful
  • Outcome: Patient remained well on follow-up

Final Outcome
  • Both episodes revealed node-negative colon cancer
  • Adjuvant therapy: Chemotherapy or radiotherapy not indicated
  • Current Status: Patient is asymptomatic and in good health

Take-Home Message
  • Patients with colon cancer have an increased risk of developing subsequent (metachronous) colorectal malignancies, especially in the presence of multiple polyps.
  • Regular colonic surveillance and follow-up are essential for early detection.
  • Synchronous and metachronous colon cancers may indicate an underlying familial or genetic predisposition, warranting genetic counseling and family screening.



    Metachronous Colon Cancer Case | Dr. Harshal Rajekar


    Metachronous Colon Cancer Case | Dr. Harshal Rajekar

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