- Case Title: Metachronous Colon Cancer
- Final Diagnosis: Moderately Differentiated Adenocarcinoma of Colon (Node Negative, T2N0M0)
Patient Profile
- Age/Sex: 59-year-old male
Presenting Complaints:
- Anemia
- Mild weight loss and generalized weakness
Initial Evaluation
- Stool Occult Blood: Positive
Colonoscopy Findings:
- Mass lesion at the splenic flexure (suggestive of colon cancer)
- 10–12 polyps distributed along the right colon
- PET-CT Scan: Node-negative localized disease
First Surgery
- Procedure Performed: Laparoscopic Left Hemicolectomy with Diverting Loop Ileostomy
- Position: Supine with right tilt
- Specimen Retrieval: Through a small epigastric incision
- Histopathology: Moderately differentiated adenocarcinoma
Postoperative Course:
- Ileostomy closure after 5 weeks
- Recovery: Uneventful
- Status: Patient remained well post-procedure
Second Presentation (8 Months Later)
- Symptoms: Rectal bleeding with a drop in hemoglobin
- Colonoscopy Findings: New tumor in the cecum
- PET-CT: Node-negative localized disease
Second Surgery
- Procedure: Total Colectomy (Open Surgery)
- Recovery: Smooth and uneventful
- Outcome: Patient remained well on follow-up
Final Outcome
- Both episodes revealed node-negative colon cancer
- Adjuvant therapy: Chemotherapy or radiotherapy not indicated
- Current Status: Patient is asymptomatic and in good health
Take-Home Message - Patients with colon cancer have an increased risk of developing subsequent (metachronous) colorectal malignancies, especially in the presence of multiple polyps.
- Regular colonic surveillance and follow-up are essential for early detection.
- Synchronous and metachronous colon cancers may indicate an underlying familial or genetic predisposition, warranting genetic counseling and family screening.

